Torrisi C, et al. - In this retrospective review, researchers determined the frequency, natural history and factors associated with the presence of transient hepatic enhancement difference showing hypointensity on hepatobiliary phase images of gadoxetic acid-enhanced MRI. For this investigation, gadoxetic acid-enhanced MRI of 125 patients with transient hepatic enhancement difference was retrospectively reviewed. Results of this study suggested that transient hepatic enhancement difference observations showing hypointensity on hepatobiliary phase images of gadoxetic acid-enhanced MRI were not infrequent and could shrink at follow-up and they were more likely related to size ≥ 21 mm, hyperintensity on T2-weighted images and previous treatment of adjacent tumor.