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Gabapentin as an adjunct to paracervical block for perioperative pain management for first-trimester uterine aspiration: A randomized controlled trial

American Journal of Obstetrics and Gynecology Jul 29, 2020

Hailstorks TP, Cordes SMD, Cwiak CA, et al. - In view of the established benefits of gabapentin as an adjunct to pain management in gynecologic surgery, researchers here examined its impact on perioperative pain during surgical management of first-trimester abortion or early pregnancy loss with uterine aspiration under local anesthesia. In this randomized double-blinded placebo-controlled trial, individuals receiving a first-trimester uterine aspiration under paracervical block in an outpatient ambulatory surgery center were randomized of receive gabapentin 600 mg 1 to 2 hours preoperatively. Outcomes revealed no reduction in pain during uterine aspiration in correlation with receiving preoperative gabapentin. However, it was associated with reduced postoperative pain, which may prove to be a desired attribute of its use, especially in patients where postoperative pain may be a greater challenge.

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