Yacovelli S, Grau LC, Hozack WJ, et al. - This study was intended to correlate the outcomes of individuals who had undergone total knee arthroplasty (TKA) using either a Posterior stabilized (PS) or cruciate-substituting (CS) insert. Researchers examined a consecutive series of 5,970 individuals who had undergone a cruciate-sacrificing TKA and received either a PS (3,314) or CS (2,656) polyethylene liner. Demographics, Knee Injury, and Osteoarthritis Outcome Score Jr (KOOS Jr), Short-Form 12 (SF-12) scores, and revision rates were compared between the groups at a minimum 2 years followup. Multivariate regression was performed to identify the independent effect of design on functional outcomes. At short-term follow-up, individuals who undergo TKA with a CS polyethylene insert have comparable functional outcomes and revision rates to those with a PS design. Longer follow-up is required to ascertain if CS can match the outstanding track record of PS TKA.