Fuentes-Abolafio IJ, Stubbs B, Pérez-Belmonte LM, et al. - Researchers sought to summarize and synthesize the data from the previous review regarding the functional objective parameters derived from an instrumented kinematic assessment which could differentiate patients with mild cognitive impairment (MCI) from cognitively healthy people, and to assess the level of evidence per outcome via this systematic review and meta-analysis. From inception to August 2019, major electronic databases were searched for cross-sectional studies published after 2015 evaluating kinematic gait and balance parameters, which may distinguish patients with MCI from cognitively healthy people. The sample consisted of 1,405 patients with MCI and 2,277 cognitively healthy people from 10 cross-sectional studies. The present analysis reveals kinematic gait parameters can discriminate patients with MCI from cognitively healthy people. A low level of evidence per outcome was seen in the grading of the assessment, development and evaluation criteria of recommendations, even though most of the included studies showed a low risk of bias.