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Functional and metabolic imaging in transthoracic biopsies guided by computed tomography

European Radiology Jan 10, 2020

Zurstrassen CE, Tyng CJ, Guimarães MD, et al. - Researchers evaluated tissue samples after who undergone biopsies led by either magnetic resonance diffusion (DWI-MR) or PET-CT findings in order to assess the histopathological outcomes on the basis of findings on apparent diffusion coefficient (ADC) and standard uptake value levels in lung lesions suspected for primary cancer. Individuals had a median lesion size of 78.0 mm, who undergone DWI-MR. For cancer regions of higher suspicion (HSA) had a median ADC of 1.1 × 10-3 mm2/s, while areas of lower suspicion (LSA) had a median ADC of 1.8 × 10-3 mm2/s. All HSA samples and 71.43% of LSA samples were positive. Overall, the use of DWI-MR and PET-CT revealed that tumors were functional and metabolically heterogeneous and that this heterogeneity had implications for histopathological diagnosis.
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