Xiao YF, Wu ZX, He S, et al. - In terms of gastrointestinal examination and lesion detection, fully automated magnetically controlled capsule endoscopy (FAMCE) performs similarly to conventional transoral gastroscopy. It can also provide a thorough inspection of the small bowel. As a result, FAMCE may be a useful approach for examining the gastrointestinal tract.

• One hundred fourteen patients (mean age 44·0 years [IQR 34·0–55·0]; 63 [55%] female) were enrolled between May 12 and August 17, 2020.

• FAMCE detected all gastric anatomical structures 100% of the time.

• Findings revealed that the concordance between FAMCE and conventional transoral gastroscopy was 99·61%.

• The mean completion time of a gastroscopy with FAMCE was 19·17 min, vs 5·21 min for conventional transoral gastroscopy.

• FAMCE and conventional transoral gastroscopy detected 214 lesions in 114 patients.

• One hundred ninety-three of these were discovered by both modalities.

• FAMCE missed five pathologies (four cases of gastritis and one polyp), compared with 16 pathologies missed by conventional transoral gastroscopy (12 cases of gastritis, one polyp, one fundal xanthoma, and two antral erosions).

• FAMCE was able to conduct a full small bowel examination of all 114 patients, and 50 (44%) of them had intestinal lesions.

• Two patients (2%) experienced adverse events during the research.

• There were no major side effects reported, and no evidence of capsule retention was seen.