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Frontal fibrosing alopecia: Demographic and clinical characteristics of 490 cases

Journal of the European Academy of Dermatology and Venereology Jul 05, 2019

Kanti V, et al. - In this observational, cross-sectional and descriptive study, researchers identified demographic and health characteristics correlated with the severity of frontal fibrosing alopecia (FFA). Participants in the study were 490 patients. Abnormal blood lipid levels have been observed in 42% of tested men and 47% of women. Thyroid disease was the most common comorbidity, with proportions higher than in the European population, possibly reflecting the role of thyroid hormones in FFA pathogenesis. Further trials need to explore the connection of abnormal testosterone and oestrogen values with lesser disease activity. The correlation analyses do not support the FFA pathophysiology role of leave-on cosmetic products.
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