Llao I, et al. - Researchers investigated the link between renal function and outcomes in patients with acute coronary syndromes (ACS) according to frailty status by using the LONGEVO-SCA registry, which included unselected patients with ACS aged ≥ 80 years. They used the FRAIL scale to evaluate the frailty status. They also calculated baseline creatinine clearance using the Cockroff-Gault formula. Furthermore, using the Cox regression method, they determined the influence of renal function on mortality or readmission at 6-months according to frailty status. According to findings, renal function impairment was detected at admission in the majority of patients aged ≥ 80 years with NSTEACS. They noted variability in the link between renal function and outcomes according to frailty status. Only patients without frailty showed a significant link between estimated glomerular filtration rate and outcomes.