Faateh M, Kuo PL, Dakour-Aridi H, et al. - Researchers inquired about the link between five-item modified frailty index (5mFI), functional status, and perioperative results among patients who had undergone carotid artery stenting (CAS) in the Vascular Quality Initiative from November 15, 2016 to December 31, 2018. In-hospital stroke or death within 30 days post-CAS, a prolonged postoperative stay (≥2 days), and non–home discharge, all were considered as perioperative outcomes. There were 7836 patients in total, of these, perioperative stroke or death occurred in 188 (2.4%), a non–home discharge was needed in 765 (9.8%), and 2584 (33.0%) had needed a prolonged postoperative stay. Findings revealed that perioperative stroke or death, non–home discharge, and an increased length of stay in patients undergoing CAS were independently predicted by frailty, as measured using the 5mFI, as well as by functional status. Among asymptomatic cases, these findings were greatly pronounced. These observations caution against the employment of CAS for asymptomatic frail patients.