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Fracture prevention by screening for high fracture risk: A systematic review and meta-analysis

Osteoporosis International Dec 19, 2019

Merlijn T, et al. - Researchers conducted this systematic review and meta-analysis to analyze the impact of population screening for high fracture risk and subsequent treatment vs usual care on all fractures, osteoporotic fractures, major osteoporotic fractures, and hip fractures. One thousand one hundred eighty-six potentially eligible articles were identified and three randomized studies were included: the ROSE study, the SCOOP study, and the SOS with a total number of N = 42,009 candidates. Meta-analysis displayed a statistically significant and clinically relevant decline of osteoporotic fractures, major osteoporotic fractures, and hip fractures, but no decrease of all fractures. The authors demonstrated the effectiveness of population screening in reducing osteoporotic fractures and hip fractures. Screening implementation in older women should be viewed as a serious option to prevent osteoporotic fractures, particularly hip fractures.
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