Aubin H, et al. – The physicians conducted this study to describe their four–year experience of providing advanced mechanical circulatory support for out–of–center patients within the Düsseldorf extracorporeal life support Network (DELSN). They illustrated that although patient selection criteria and early outcome parameters reflecting on therapy success or futility were yet to be refined, regional mobile extracorporeal life support (ECLS) rescue therapy could be provided with encouraging outcomes.