Fakih R, et al. - In this Comprehensive Longitudinal Investigation of Multiple Sclerosis (MS) at the Brigham and Women’s Hospital (CLIMB) study, researchers evaluated the correlation between a self-reported history of allergic conditions with multiple sclerosis (MS) clinical and MRI disease activity. Study participants included 1349 patients who completed a self-administered questionnaire on environmental, food and drug allergies. Compared to patients with no known allergy, MS patients with food allergy had more relapses and a higher likelihood of gadolinium-enhancing lesions. The observed that the expanded disability status scale (EDSS) and MS severity score (MSSS) were not affected by any type of allergy.