Juujärvi S, et al. - In this follow-up of the 2013-2014 randomized, double-blind Preterm Infant's Paracetamol Study at Oulu University Hospital, Finland, researchers investigated the long-term outcomes and safety of early intravenous paracetamol for ductus arteriosus closure at a corrected age of two years. They assessed 48 very preterm infants within 24 hours of birth who were administered intravenous paracetamol or a placebo for four days and were then followed up. No differences were found in cardiac parameters (blood pressures and ultrasound scan results), and no signs of autism were reported. Two years later, no long-term adverse reactions of early intravenous paracetamol were seen.