Kemper JI, Li W, Goni S, et al. - The selection of the studies was carried out using Cochrane Review on Mechanical Methods for Induction of Labour, Ovid MEDLINE, Embase via Ovid, Ovid Emcare, CINAHL Plus, ClinicalTrials.gov and Scopus from inception to April 2019 to compare the safety and efficacy of Foley catheter and oral misoprostol use in induction of labor (IOL). The quality of included randomized controlled trials was evaluated using the Cochrane Risk of Bias 2 tool and the certainty of the evidence was assessed utilizing the GRADE approach. The sample consisted of 2,815 participants, of which 1,399 women were assigned to the Foley catheter and 1,416 to oral misoprostol. The Foley catheter is less effective than oral misoprostol in women undergoing IOL as it was linked to fewer vaginal births. However, although the authors found no significant variation in maternal safety, Foley catheter induction may lessen adverse perinatal outcomes.