Nassiri N et al. – This study assessed the eligibility for focal therapy (FT) in men who receive multiparametric magnetic resonance imaging (mpMRI) and targeted biopsy, with correlation to whole mount histology following radical prostatectomy (RP). The authors concluded that using intermediate–risk eligibility criteria, more than one third of men in whom targeted biopsy–proven lesion was identified on mpMRI would be eligible for FT. In addition, 75% of the cases showed concordant findings for eligibility determined by fusion biopsy and whole mount histology. However, improved selection criteria are required to reliably determine eligibility for FT.