van Luijtelaar A, Greenwood BM, Ahmed HU, et al. - A panel of international specialists in the field of focal therapy (FT) in prostate cancer (PCa) carried out a collaborative consensus project using the Delphi method in order to explain the role of focal laser ablation (FLA) as clinical treatment of PCa using the Delphi consensus method. Thirty-seven experts accepted to take part, and the consensus was attained on 39/43 topics. FLA was optimal for targeted ablation of a specific MRI-visible focus, in individuals with intermediate-risk PCa (Gleason score [GS] 3+4) as well as cases with MRI-visible and biopsy-confirmed local recurrence. Nevertheless, FLA should not be employed to candidates for active surveillance and close follow-up is needed. Appropriateness for FLA is on the basis of tumor volume, location to vital structures, GS, MRI-visibility, and biopsy confirmation. Thus, focal laser ablation was observed to be a promising method for the treatment of clinically localized PCa and should ideally be done within established clinical trials. So far, only a few studies have published on FLA and further verification with longer follow-up is necessary before widespread clinical implementation is supported.