Fluid overload in special pediatric cohorts with anomalous origin of the left coronary artery from the pulmonary artery following surgical repair
Journal of Cardiothoracic and Vascular Anesthesia Nov 28, 2019
Wang J, Wang C, Wang Y, et al. - Researchers performed this retrospective study with a special group of pediatric patients undergoing repair of anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA), to determine the prevalence, risk factors, as well as clinical results related to early fluid overload (FO) in this population. In this study done with multiple variable regression analysis, they included 88 patients younger than 18 years of age recruited at the authors’ institution from June 2010 to September 2017. Being underweight was corroborated to be a risk factor for FO development, with logistic regression analysis. Severe acute kidney injury, respiratory morbidity, and low cardiac output syndrome following reimplantation procedure were predicted by early FO. In pediatric patients undergoing repair for ALCAPA, early FO ≥ 5% has been associated with adverse postoperative consequences. Findings also highlighted the importance of the use of restrictive fluid management in cases with lower weight and poor myocardial function prior to and following complex surgical procedures such as in ALCAPA settings.
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