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Fluid management in patients undergoing cardiac surgery: Effects of an acetate- vs lactate-buffered balanced infusion solution on hemodynamic stability (HEMACETAT)

Critical Care May 10, 2019

Pfortmueller CA, et al. - Given that the choice of buffer in balanced crystalloid solutions may alter their hemodynamic impacts, researchers used a randomized controlled double-blind design and compared the inopressor demands of Ringer’s acetate and lactate for perioperative fluid management in patients undergoing cardiac surgery. This study included patients undergoing elective valvular cardiac surgery and excluded patients were those having severe cardiac, renal, or liver disease. In a random fashion, Ringer’s acetate was used in 75 cases and Ringer’s lactate in 73. Both the groups demonstrated comparable hemodynamic profiles. In addition, a similar evolution of acid-base parameters was observed.
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