Fluid balance and recovery of native lung function in adult patients supported by venovenous extracorporeal membrane oxygenation and continuous renal replacement therapy
ASAIO Journal Aug 02, 2019
McCanny P, et al. - Researchers examined how early fluid removal impact survival and lung recovery in adult patients supported by venovenous extracorporeal membrane oxygenation (VV-ECMO) and concomitant continuous renal replacement therapy, in an 18-bed tertiary intensive care unit between 2010 and 2015. They included 24 patients in this work; survival to hospital discharge was reported in 15 of these (63%). In this patient group, improved pulmonary compliance was observed in strong correlation with a more negative cumulative daily fluid balance. Further, there was an association of a more negative mean daily fluid balance with improved pulmonary compliance. Survivors were noted to be younger along with having lower mean daily fluid balance and lower cumulative fluid balance up to day 14, however, the fluid balance effect alone did not reach statistical significance.
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