Reznik ME, Daiello LA, Thompson BB, et al. - Using a single-center ICU database, researchers compared stroke patients vs non-neurological patients in terms of links between fluctuating consciousness and Confusion Assessment Method for the Intensive Care Unit (CAM-ICU) evaluations. Participants were patients with stroke or sepsis, for whom all recorded CAM-ICU assessments were joined to corresponding Richmond Agitation Sedation Scale (RASS) measurements. They defined fluctuating consciousness by RASS variability utilizing standard deviations (SD) over 24-h durations. Higher odds of positive and “unable to assess” CAM-ICU ratings were observed among stroke patients vs sepsis patients, and higher RASS variability was reported for CAM-ICU-positive and UTA (unable to assess) assessment-days vs CAM-ICU-negative assessment-days, particularly in stroke patients. According to the findings, delirium after stroke may often go unrecognized by the CAM-ICU, even in the setting of fluctuating consciousness.