Davierwala PM, Marin-Cuartas M, Misfeld M, et al. - Researchers investigated the 5-year outcomes in patients undergoing a complex operation involving radical debridement of all infected tissue, followed by double valve replacement (aortic and mitral valve replacement) with patch reconstruction of the intervalvular fibrous body (IFB) for treatment of double valve infective endocarditis (IE) with IFB involvement. They assessed a total of 127 consecutive patients (mean age: 65.3 ± 12.9 years) who underwent this procedure between January 1999 and December 2018. They identified preoperative cardiogenic shock and sepsis in 17.3% and 18.9%, respectively. They identified double valve replacement with reconstruction of the IFB as a challenging operation in patients with complex IE; this procedure is linked with high morbidity and mortality, especially in the first 90 days after surgery. Findings suggest survival and freedom from reoperation rates as acceptable thereafter, particularly considering the severity of disease and complex surgery.