Räber L, et al. - Researchers compared outcomes of biolimus-eluting stents (BESs) with biodegradable polymer vs bare-metal stent (BMS) during a 5-year clinical follow-up of 1,157 patients with ST-segment elevation myocardial infarction (STEMI) included in the randomized COMFORTABLE AMI trial. Overall 575 patients were treated with BES and 582 with BMS. At baseline and 13 months follow-up, both intravascular ultrasound (IVUS) and optical coherence tomography were used to perform serial intracoronary imaging of stented segments and findings were analyzed in 103 patients. A lower 5-year rate of major adverse cardiac events (MACE) was observed in relation to implantation of biodegradable polymer-coated BES vs BMS. Regardless of stent type, nearly complete vascular healing was observed at 13 months in treated culprit lesions.