Cohen O, Amos I, Halperin D, et al. - A retrospective study in a single, academic institution was conducted to evaluate the 5- and 10-year success rates of endoscopic dacryocystorhinostomy (eDCR), and its associated risks. Between the years 2002–2017, all eDCRs conducted at Kaplan Medical Center were involved. Three hundred twenty-one, 168, and 65 patients were included for immediate, 5- and 10-year outcome analysis, respectively, after exclusions. Overall success rates, respectively, were 92.5%, 86.3%, and 80%. Data reported that the anatomical success rates, respectively, were 93.8%, 89.9%, and 86.1%. Findings suggested that eDCR is advantageous for the majority of patients also at 10 years following surgery in spite of reduced rates over time. Older age, smoking, postoperative epiphora, and male gender are related to long-term failure and should be addressed before surgery with patients.