Wang HY, Yuan MC, Pei FZ, et al. - In this study, the optimal level of blood pressure control during no tourniquet total knee arthroplasty (TKA) surgery with the use of tranexamic acid in this study was investigated. Researchers classified individuals who had undergone TKA into three groups: the mean intraoperative systolic blood pressure in group A was < 90 mmHg, 90–100 mmHg in group B, > 100 mmHg in group C. They recorded total blood loss, intraoperative blood loss, hidden blood loss, transfusion rate, maximum hemoglobin drop, operation time, and postoperative hospitalization days. They included a total of 278 patients, It was shown that systolic blood pressure from 90 to 100 mmHg was the optimal strategy for no tourniquet primary TKA with tranexamic acid.