Yoon BH et al. – This study determined the femoral head trabecular microarchitecture in patients with osteoporotic hip fractures based on their history of bisphosphonate treatment (BT). The results concluded that bisphosphonate treatment preserved bone mass and bone quality; however, further research is required to confirm the findings.

Methods

• A total of 133 patients with hip fractures were included and divided into 2 groups based on whether they had received treatment with bisphosphonates for >3 years or not (non–bisphosphonate–treated patients [NT]).
• In total, 15 matched pairs of patients were identified based on one–to–one propensity score matching.

Results

• In the BT group, trabecular bone pattern factor and specific bone surface were significantly lower compared to the NT group.
• Young's modulus was significantly higher in the BT group compared with the NT group.
• Trabecular bone pattern was identified to be the most closely correlated microstructural parameter to bone strength in both groups.
• Bone connectivity was better preserved in the BT group than in the NT group.