Waltuch T, Gill P, Zinns LE, et al. - Researchers sought to describe four previously healthy children with COVID-19 infection confirmed by serologic antibody testing, but negative by nasopharyngeal RT-PCR swab, presenting to their New York City Pediatric Emergency Department (PED) nearly 1 month from the peak of 6,207 new COVID-19 cases reported on April 6, 2020. In all these patients, development of similar multi-system, inflammatory state requiring admission to the Pediatric Intensive Care Unit (PICU) was observed. These patients showed quick decompensation and required admission to monitor for stability. Findings suggest COVID-19 post infectious cytokine release syndrome as a novel disease in children. The patients with this syndrome had features similar to Kawasaki Disease and Toxic Shock Syndrome. Features comprised prolonged fever, gastrointestinal symptoms with or without rash.