Zaouter C, et al. - Researchers examined the feasibility of closed-loop sedation, defined as successful automated sedation without manual override, in patients undergoing elective transcatheter aortic valve implantation (TAVI). Secondary qualitative observations were clinical and controller performance. As per investigators' observations, the automated closed-loop sedation system tested could be used successfully for patients scheduled for a TAVI procedure. Furthermore, a satisfactory clinical performance of sedation control was demonstrated.