Boughdad S, O'Connor A, Cook GJ, et al. - Because recent developments in novel radiotracers have called into question the utility of FDG PET-CT in head and neck paragangliomas (HNPGLs), researchers conducted a retrospective study in a single tertiary referral centre to address the utility of FDG PET/CT in HNPGLs. From 2004 to 2016, clinical data on genetic testing and follow-up were obtained for patients who had FDG PET-CT scans. Of the 153 HNPGL patients, 73 (29 SDHx+) had 93 FDG-positive lesions: 53.8% of lesions were evaluated in a pre-therapeutic setting. FDG PET-CT showed good performance to detect HNPGLs (96.6% accuracy) in comparison with a reference extracted from the clinicoradiological database. FDG PET-CT has clinical utility in HNPGLs, primarily prior to local treatment. PET parameters did not differ significantly between SDHx patients and a sporadic HNPGL population. A high SUVmax, regardless of SDHx mutation status, was associated with more clinical events and prompts a closer follow-up.