Millot F, et al. - Via a study of 479 children and adolescents with childhood chronic myeloid leukemia (CML) presenting at diagnosis with advanced phase disease, the researchers intended to report the experience within the I-CML-Ped study and to describe their characteristics and outcomes. Five-year overall survival rates as 94% and 74% for patients diagnosed in CML-accelerated phase and CML-blastic phase, respectively were noted. Hence, it was concluded that children with advanced phase at diagnosis of CML seemed to have a better survival rate than that reported for advanced phases evolving under tyrosine kinase inhibitors treatment.