Aiderus A, et al. - Researchers assessed how fatty acid metabolism and outcome in breast and other cancers are linked. They identified genesets associated with outcome by using Cox regression analysis and Gene Set Enrichment Analysis of a gene expression dataset from primary breast tumors with well annotated clinical and survival information. Thereafter, they assessed a geneset representing fatty acid oxidation (FAO) in other datasets. Findings suggested the downregulation of FAO in multiple tumor types. Results also suggested that cancer cell proliferation may be lowered by the activation of this pathway. Such an activation was found to be related to improved outcomes in some cancers.