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Fat mass accretion from birth to 5 years and metabolic homeostasis in childhood: The Healthy Start Study

Journal of Clinical Endocrinology and Metabolism Feb 26, 2021

Sauder KA, Perng W, Palumbo MP, et al. - As it is uncertain how fat mass accretion in early life is associated with glucose-insulin homeostasis, researchers sought to investigate correlations of fat and fat-free mass accretion from birth to early childhood with glucose-insulin homeostasis in early childhood in a multi-ethnic cohort. Participants in the study were 419 mother/offspring dyads. In children of Hispanic, Black, and Other races/ethnicities at 5 years of age, greater fat mass accretion in infancy and childhood is linked to shifts in fasting glucose. For metabolic health, body composition beginning in early life is relevant, and precise adiposity assessments are required in pediatric research.

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