Tohidi M, et al. - In Iranian adults during a median follow-up of 12 years, researchers compared the effect of triglyceride–glucose index (TyG-index), the product of fasting plasma glucose (FPG) and triglycerides (TG) with FPG, 2 h post-challenge plasma glucose (2 h-PCPG), TG/high-density lipoprotein cholesterol (TG/HDL-C), and homeostasis model assessment of insulin resistance (HOMA-IR) indices for prediction of type 2 diabetes (T2D). Participants in the study were 4419 (1858 men) subjects with a mean age of 40.6 ± 13.2 years. As compared to the TyG-index, TG/HDL-C, and HOMA-IR indices, FPG was a stronger predictor of T2D. In spite of the fact that TyG-index was superior to TG/HDL-C in both genders, it did not rank above HOMA-IR.