Bancks MP, et al. – Researchers conducted this study to determine if intraindividual variability in fasting glucose (FG) below the threshold of diabetes is correlated with cognitive function in middle adulthood beyond increasing FG. For this investigation, data from 3,307 CARDIA participants (age range, 18–30 years; 1985–1986) were examined at baseline, and the investigators calculated two measures of long-term glucose variability: the coefficient of variation about the mean FG and the absolute difference between successive FG measurements (average real variability) before the onset of diabetes over 25 and 30 years of follow-up. Findings suggested an association of higher intraindividual FG variability during young adulthood below the threshold of diabetes with worse processing speed, memory, and language fluency in midlife independent of FG levels.