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Failure to predict high-risk Kawasaki disease patients in a population-based study cohort in Germany

The Pediatric Infectious Disease Journal Aug 21, 2018

Jakob A, et al. - Researchers ascertained whether Kobayashi, Egami and Sano scores or application of up-to-date statistical methods (Random Forest) could predict response to standard intravenous immunoglobulin (IVIG) therapy and the risk of persistent coronary artery aneurysm (CAA) in patients with Kawasaki disease (KD) in a mainly Caucasian population in Germany. For this study, 301 children were eligible for assessment of their response to IVIG treatment. The present data indicated that none of the available scores seems to be appropriate for identifying high-risk Caucasian children with KD who might need intensified therapy.

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