Jung Y, et al. - In this prospective clinical study, researchers assessed factors predictive of en bloc and complete resection of large colorectal neoplasms using hybrid endoscopic submucosal dissection (ESD). Between May 2015 and September 2016, 78 patients underwent hybrid ESD for excision of colorectal neoplasms (≥ 2 cm) at six university hospitals, and they were included in this study. Study results showed that visualization during snaring, presence of fibrosis, gross lesion type, and endoscopist colorectal ESD experience level affect en bloc or complete resection of large colorectal neoplasia using hybrid ESD.