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Factors associated with response to teduglutide in patients with short-bowel syndrome and intestinal failure

Gastroenterology Nov 30, 2017

Jeppesen PB, et al. - A post-hoc analysis of phase 3 placebo-controlled study was performed to identify characteristics of patients in whom teduglutide has the largest effects on parenteral support volume response. The researchers associated reduced parenteral support volume with baseline parenteral support volume, bowel anatomy, and short bowel syndrome (SBS) features. These findings could inform initial parenteral support volume adjustments and management of these severely disabled patients.
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