Barbera L, et al. - Researchers examined opioid use in cancer survivors of more than 5 years without recurrence in order to determine the factors linked with its use. Exposures of opioid use before cancer diagnosis, opioid use between cancer diagnosis and 5-year anniversary, surgeries, and chemotherapy were also investigated. The study sample consisted of a retrospective cohort of 7,431 individuals. Increased risk of continued use after 5 years of survival was evident among patients who used opioids continuously between diagnosis and index date. Higher risk of post–index date opioid use was also noted in correlation with a history of depression, comorbidity, and more than 2 years of diabetes. Prior opioid use was associated with opioid use between diagnosis and index. Findings highlighted safe and appropriate pain management as a significant survivorship issue.