Gebre BB - Researchers sought to evaluate the magnitude of alcohol use among HIV/AIDS positive adults visiting ART clinic at Mizan Tep University Teaching Hospital, Southern Ethiopia from October 2017 to December 2017. Further, they sought for the associated factors. In this facility-based cross-sectional study of a sample of 332 HIV positive adults, alcohol use disorder (AUD) was prevalent in 18.4% of the participants. This suggests a high prevalence of AUD in this population. Male gender AOR = 3.48 (95% CI: 1.27, 9.59), cigarette smoking AOR = 5.12 (95% CI: 4.02, 8.61), “khat” chewing AOR = 3.23 (95% CI: 2.06.6.89), and CD4 count of 0–200 AOR = 19.49 (95% CI: 1.74, 218.4) were the factors associated with AUD.