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Factors associated with acute kidney injury during delivery or the postpartum period: A case control study

European Journal of Obstetrics & Gynecology and Reproductive Biology May 04, 2021

Coles H, Steer P, Hughes P, et al. - Researchers undertook this retrospective case control study to determine incidence of risk factors related to acute kidney injury (AKI) occurring during the intrapartum or the immediate postpartum period. They performed a comparison between women with pregnancy related AKI (pr-AKI) in labour or postpartum vs a matched cohort of women with no evidence of pr-AKI, applying multiple regression. They identified 1.5% of this cohort developed Pr-AKI, thus, this condition was relatively common. The observed risk was the greatest among women who were overweight, had prolonged rupture of the membranes, an emergency caesarean section and/or a postpartum haemorrhage. In the presence of risk factors for AKI, clinicians are advised to assess kidney function prior to prescribing non-steroidal medication for postpartum pain relief.

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