Zhang T, et al. - In order to gain insights into the clinical characteristics, stage, treatment, and prognosis of extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma), researchers performed this retrospective study including 105 patients with MALT lymphomas in the oromaxillofacial head and neck region. They assessed complete response (CR) rate, overall survival, and progression-free survival (PFS) as primary endpoints. According to the findings, satisfactory outcomes were achieved following the initial treatment of MALT lymphomas in the oromaxillofacial head and neck region. A slow progression of this disease was evident. Localized lymphoma patients vs disseminated lymphoma patients exhibited better CR rate and PFS. In disseminated disease patients, an improved PFS may be achieved with systemic treatment (chemotherapy or rituximab). The identified independent prognostic factors were MALT Lymphoma International Prognostic Index and Ann Arbor staging.