Zumbo G, et al. - In this present study, the authors describe the relationship between the bolus-only and current gold-standard infusion extracellular volume (ECV) in patients with amyloidosis. The bolus-only technique in amyloidosis, with large ECVs, reads higher in comparison to the infusion technique, but the clinical performance by any measure is the same. In view of the work-flow advantages, these data suggest that for amyloidosis, the bolus-only approach can be acceptable and may support its use as a surrogate endpoint in future clinical trials.