Extending visit intervals for clinically stable patients on antiretroviral therapy: Multicohort analysis of HIV programs in Southern Africa
Journal of Acquired Immune Deficiency Syndromes Jul 01, 2019
Haas AD, et al. - In antiretroviral therapy (ART) programs in Southern Africa, time trends in visit frequency and links between criteria for clinical stability and visit frequency were examined via adults on ART (n=180,837) from four programs with viral-load monitoring, two programs with CD4 monitoring, and four programs with clinical monitoring of ART. Patients were categorized as clinically stable based on virological (viral load <1,000 copies/mL), immunological (CD4 >200 cells/µL), or clinical (no current tuberculosis) criteria. Findings revealed variable and overall modest differences in visit rates between stable patients and patients failing ART. Programs using virological criteria for clinical stability vs programs using immunological criteria showed larger differences. Increase in scale-up of differentiated ART delivery could be achieved via greater access to routine viral-load monitoring.
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