Expression patterns of Toll like receptor (TLR)-2, TLR-4 and myeloid differentiation primary response gene 88 (MYD88) in renal transplant patients developing allograft dysfunction: A cohort study
Transplant Immunology Feb 20, 2018
Hosseinzadeh M, et al. - Researchers sought to determine the sequential dynamic changes in Toll-like receptor (TLR)-4, TLR-2, and myeloid differentiation primary response gene 88 (MYD88) mRNA expressions in peripheral blood mononuclear cells (PBMCs) and biopsy samples from kidney allograft recipients in relation to graft function. As per their observations, for early and late kidney allograft function, sequential monitoring of the expression patterns of TLR-2, TLR-4, and MYD88 in PBMCs and biopsy samples could be considered as predictive biomarkers.
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