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Expression of vimentin (VIM) and metastasis-associated 1 (MTA1) protein in laryngeal squamous cell carcinoma are associated with prognostic outcome of patients

American Journal of Otolaryngology - Head and Neck Medicine and Surgery Jun 15, 2019

Karamagkiolas S, et al. - Using immunohistochemistry, researchers studied the potential combinatorial prognostic value of NOTCH1, Vimentin (VIM), and Metastasis-associated 1 (MTA1) protein in laryngeal squamous cell carcinoma (LSCC), a common type of head and neck cancer. Participants in the study were 69 patients with LSCC. According to findings, VIM and MTA1 are potential LSCC tumor biomarkers and can be integrated into a multiparametric prognostic model. Undoubtedly, in larger cohorts of LSCC patients, their prognostic value needs further validation.
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