Tangen IL, et al. - A scrutiny was carried out of the expression of glucocorticoid receptor (GR) in primary and metastatic endometrial cancer lesions. Furthermore, the authors sought to discern the link between GR expression and clinical and histopathological variables and survival. The findings brought to light the connection between GR expression in primary endometrial cancer with aggressive disease and poor survival. Maximum metastatic endometrial cancer lesions expressed GR. Hence, it was noted that GR could represent a therapeutic target in the adjuvant therapy of poor prognosis early-stage and metastatic endometrial cancer.