Deziel NC, et al. - In view of the three times higher rates of thyroid cancer incidence among women vs men, researchers sought to examine if this trend is related with exposure to thyroid hormone-disrupting flame-retardant chemicals, including polybrominated diphenyl ethers (PBDE) and polybrominated biphenyls (PBB). They assessed 250 incident female papillary thyroid cancer cases and 250 female controls for this work. In single-pollutant models, they observed a reduced risk at the highest (> 90th percentile) vs lowest (< median) category of BDE-209 concentrations; a raised papillary thyroid cancer (PTC) risk was noted at the highest vs lowest category of BB-153 concentrations. Evidence gained do not generally support a positive relationship between PBDE/PBB and PTC risk.