Abraham JR, Wykoff CC, Arepalli S, et al. - This research examines the correlation of intraocular cytokine expression and ultrawide-field fluorescein angiography (UWFA) quantitative imaging biomarkers and their relationship with angiographical feature response after antivascular endothelial growth factor (VEGF) therapy in diabetic macular oedema. Through multiplex arrays, 54 cytokines associated with inflammation and angiogenesis were assessed. Twenty-one eyes were involved with a mean age of 55 ± 10 years. Multiple aqueous humour cytokine concentrations, including VEGF and IL-6, were correlated with baseline and longitudinal quantitative UWFA imaging parameters. More research is needed to determine the implications of using these findings to evaluate treatment response.