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Exploration of the role of anti-Mullerian hormone and LH/FSH ratio in diagnosis of polycystic ovary syndrome

Clinical Endocrinology Feb 14, 2019

Le MT, et al. - In this multicentre cross-sectional descriptive study, researchers examined the role of anti-Mullerian hormone (AMH) and LH/FSH ratio in the diagnosis of polycystic ovary syndrome (PCOS). In three infertility centres in Vietnam, a total of 863 infertile women (aged 18 to 45 years) were assessed and recruited from June 2016 to June 2017. In PCOS diagnosis, the value of serum AMH concentration was found to be not significantly higher than the LH/FSH ratio. Although these biomarkers are separately inadequate for the diagnosis of PCOS on the basis of their own value, the combination of different endocrine factors, including the AMH, LH and LH/FSH ratio, together with BMI and other anthropometric and clinical characteristics may provide additional value for the diagnosis of PCOS.
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