Exploration of BRAFV600E as a diagnostic adjuvant in the non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP)
Human Pathology Jul 12, 2018
Johnson DN, et al. - In the present study, the researchers sought to analyze BRAFV600E as a diagnostic adjuvant in the non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP). For this analysis, they assessed for BRAFV600E mutation using mutation-specific BRAF (VE1) antibody immunohistochemistry (BRAFVE) as part of an immunomorphologic tumor panel, often including HBME1, for follicular-patterned lesions with nuclear atypia. It was observed that BRAFVE used in conjunction with routine sampling of follicular-patterned tumors was a beneficial diagnostic adjuvant.
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