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Exploration of differentially expressed plasma proteins in patients with lung adenocarcinoma using iTRAQ-coupled 2D LC-MS/MS

The Clinical Respiratory Journal Jan 29, 2018

Li W, et al. - In this study, the protein profile in plasma of lung adenocarcinoma of stages I–IV were identified, and novel diagnostic biomarkers were investigated. Findings suggested that plasma SCGB3A2 affords a potential maker for diagnosis of primary pulmonary adenocarcinoma. A possible association of abnormal post-translational protein modification with the progression of lung cancer was also suggested.
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